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临床试验/NCT06217770
NCT06217770已完成不适用

Retrospective, Non-interventional Study Assessing the Real-Life Use of The Long- Acting Gonadotropin-releasing Hormone Agonist as A Treatment for Locally Advanced or Meta-static Prostate Cancer in Hong Kong.

Chinese University of Hong Kong1 个研究点 分布在 1 个国家目标入组 237 人开始时间: 2023年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
237
试验地点
1
主要终点
The usage pattern of the long-acting Gonadotropin-releasing Hormone Agonist agonist triptorelin in real-life clinical practice

研究概览

简要总结

It is a retrospective review of the electronic medical record of patients on long-acting triptorelin in Hong Kong.

详细描述

Prostate cancer is the second most prevalent cancer in men worldwide. Analogues of natural gonadotrophin releasing hormone (GnRH) are currently available in clinical practice to induce castration in subjects with prostate cancer. While 6 month formulation of Triptorelin has been approved since 2018 for controlling tumor growth in subjects with prostate cancer living in Hong Kong, to date, there are no published clinical data regarding the use and efficacy of the 6 month formulation in Chinese subjects with Chinese heritage. To better understand the real-world experience of long-acting GnRH agonist, there is an unmet need for a retrospective, noninterventional review to collect data regarding the use of the long-acting formulation GnRH in clinical practice as a treatment for prostate cancer. The purpose of this study is to collect data on healthcare characteristics and the treatment patterns in the real-world setting, as well as to understand the profile of the subject population using long-acting formulation GnRH agonist.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Patients of Chinese heritage
  • Prostate cancer patients with the following disease status:
  • High-risk prostate cancer having hormonal therapy as neoadjuvant / adjuvant treatment for prostatectomy or radiotherapy; or
  • Advanced / metastatic prostate cancer treated with long-term hormonal therapy; or
  • After primary therapy (surgery or radiotherapy) with biochemical recurrence; or
  • Castration-resistant prostate cancer status
  • Received at least one dose of 6-month Gonadotropin-releasing Hormone Agonist triptorelin formulation
  • Having at least 6 months of follow-up after administration of the 3-month to 6-month Gonadotropin-releasing Hormone Agonist triptorelin

排除标准

  • 未提供

结局指标

主要结局

The usage pattern of the long-acting Gonadotropin-releasing Hormone Agonist agonist triptorelin in real-life clinical practice

时间窗: 6 months

The duration and type of GnRH agonist

次要结局

  • The effectiveness of the long-acting Gonadotropin-releasing Hormone Agonist agonist triptorelin in inducing and maintaining castration(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Chi Fai NG

Professer

Chinese University of Hong Kong

研究点 (1)

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