Does Checklist Utilisation Decrease Complications Related to Intubation of the Critically Ill Adult? - a Two-phase Retrospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Level of desaturation
研究概览
简要总结
This retrospective study aims to explore whether the introduction of a preprocedural checklist for intubation in the intensive care unit (ICU) is associated with a lower incidence of intubation-related complications. Using a database where protocols from intubations in the ICU before implementing a checklist and after we will investigate whether a checklist affects early desaturation and hypotension after intubation.
详细描述
PROJECT PLAN
Does checklist utilisation decrease complications related to intubation of the critically ill adult? - a two-phase study
Study code: CHECC (Checklist for Endotracheal intubation in the Critical Care)
Ethical approval: This study will be conducted in accordance with GCP and National Swedish standards, as well as local standard procedures at the Clinical Research Unit at Function Perioperative Medicine and Intensive Care, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.
Principal investigator: Jessica Kåhlin, MD, PhD
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient in the ICU
- •Need for tracheal intubation
排除标准
- •Pateint is under 18 years of age
- •Patiend inclusion is decided not suitable for any reason by the intensivist
研究组 & 干预措施
Standard care
Intubation procedure before introduction of a checklist
干预措施: Checklist (Other)
Checklist group
Intubation procedure after introduction of a checklist
干预措施: Checklist (Other)
结局指标
主要结局
Level of desaturation
时间窗: From intubation up to 5 minutes after the procedure
\- Peripheral oxygen saturation (SpO2) below 90% (or \>5% drop if saturation is \<90% after preoxygenation).
Level of lowering blood pressure
时间窗: From intubation up to 5 minutes after the procedure
A systolic arterial pressure (SAP) below 90 mmHg
次要结局
- 30-day mortality(30 days)
- Days in the intensive care unit(3 months)
- Lowest median oxygen saturation(From induction of anaesthesia until up to 5 min after intubation?)
- First-pass success rate(1 hour)
- Ventilator days(30 days)
- Number of intubation attempts(1 hour)
- Number of arrythmias(Up to 5 min after intubation)
- Presence of cardiac arrest(Up to 5 minutes after intubation)
- Change of intubation method(1 hour)
- Change of operator during intubation?(During intubation)
- Intubation time(5 minutes)
研究者
Jessica Kåhlin
Research group leader
Karolinska University Hospital