Clinical Characteristics and Surgical Outcomes of Full-thickness Macular Hole Without Focal Vitreomacular Traction.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 主要终点
- postoperative visual acuity
研究概览
简要总结
This multicenter, retrospective, observational comparative study. We occasionally encounter FTMHs in which PVD has not been achieved and VMT is absent. These FTMHs cannot be defined by stage in the Gass1) or IVTS3) classification. It is not known whether traction is involved in the development of these atypical macular holes, but they are often classified as Gass stage 2 or 3 according to the size of the hole.
The aim of this study was to investigate the clinical features and surgical outcomes of FTMHs without focal VMT and to discuss possible underlying mechanisms.
详细描述
The clinical characteristics and surgical outcomes the patients diagnosed with FTMH without focal VMT in the macula (classified as VMT-) are presented, in addition to a comparative analysis of the patients presenting with classic stage 2 FTMH with focal VMT (classified as VMT+) according to international classification criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •macular hole without posterior vitreous detachment at the fovea
排除标准
- •macular hole with posterior vitreous detachment at the fovea
- •Stage1.3.4 macular hole
- •Macular hole-associated retinal detachment
- •Macular hole with subretinal hemorrhage
- •Traumatic MH
结局指标
主要结局
postoperative visual acuity
时间窗: 1month, 3, 6 and 12 months
logMAR visual acuity
次要结局
- postoperative status of outer retinal layer in OCT B-scan images(1month, 3, 6 and 12 months)
研究者
Jiro Kogo
Associate Professor
St. Marianna University School of Medicine