Effects of varenicline and cognitive bias modification on neural response to smoking-related cues

niversity of Bristol (UK)0 个研究点目标入组 72 人开始时间: 2014年1月30日最近更新: 2019年2月11日

试验速览

•1. Female volunteers who are pregnant or breast feeding
•2. Female volunteers not using adequate contraception
•3. Volunteers who do not currently have a GP
•4. Current or previous substance or alcohol misuse or dependence [other than nicotine]
•5. Alcohol use in excess of 35 Units/week if female or 50 Units/week if male
•6. Caffeine use = 8 cups per day
•7. Significant current or past psychiatric illness (Axis 1 or 2 psychiatric diagnoses) as diagnosed by a psychiatrist
•8. Clinically significant abnormality including cardiology risk factors and history of arrhythmia (as assessed by self-report)
•9. Ongoing use of medication (i.e. intake of any medication within 8 weeks of study, with exception of local treatment and occasional paracetamol or non-steroidal anti-inflammatory drugs, e.g., aspirin or ibuprofen)
•10. Smokers actively trying to give up smoking during the study period
•11. Uncorrected visual impairment (including colour-blindness)
•12. Uncorrected auditory impairment
•13. Condition that makes MRI scanning unsafe (e.g. metallic implants; history of metal-working)
•14. Unable to tolerate scanning environment (as established during a short anatomical MRI scan on day 0)
•15. Hypersensitivity to Champix

发起方

niversity of Bristol (UK)