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临床试验/NCT05529446
NCT05529446已完成不适用

Effect of Combination Therapy on Knee Osteoarthritis Pain in Postmenopausal Women

Cairo University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2022年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
Knee Range Of Motion

研究概览

简要总结

the aim of this study is to investigate the efficacy of Combination Therapy on Knee Osteoarthritis Pain in Postmenopausal Women

详细描述

Osteoarthritis (OA) is the most common musculoskeletal condition affecting the quality of life of older adults. The prevalence of OA is very high 45% in females in comparison to males, especially after menopause due to the hormonal changes. In the physical therapy practice, therapeutic ultrasound (US) is one of the most frequently applied electrotherapeutic modalities in orthopedics physiotherapy. Simultaneous application of two therapeutic modalities at the same site is described as combination therapy (CT). The most commonly used CT is US & Transcutaneous neuromuscular electrical stimulation (TENS )where this approach was effective in pain modulation .The use of combination therapy is highly preferable because of the advantageous effect both electro-therapy and ultrasound provide simultaneously. There are no current studies on using combination therapy in the treatment of pain in mild to moderate knee osteoarthritis in post-menopausal women and we don't know the proper treatment dose.The study is designed as a prospective, randomized, pre-posttest, controlled trial.where we have two groups Intervention group and control. the intervention group will recieve strengthening exercises in addition to combination therapy 10 minutes for each session, 3 times per week, for 3 weeks.The Control group will recieve the same strengthening exercises as intervention group and sham combination therapy 10 minutes for each session, 3 times per week, for 2 weeks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
55 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者
否

入选标准

  • •Forty women who suffer pain out of mild to moderate knee osteoarthritis
  • •Their age will range from 55 to 65
  • •At least one year after last menstruation.
  • •Their BMI will be ranged from 25 to 35 kg/m2

排除标准

  • •Neurological disorders.
  • •Cardiovascular disorders.
  • •Severe knee osteoarthritis
  • •Areas of the body where cancerous lesions exist.
  • •Any skin impairment at site of application as inflammation, lesion, wounds, infection and swelling.
  • •Pacemaker and any metallic implants.

研究组 & 干预措施

intervention

Experimental

This group will consist of twenty women with mild to moderate osteoarthritis suffering from pain. These women will perform strengthening exercises in addition to combination therapy 10 minutes for each session, 3 times per week, for 3 weeks.

干预措施: Combination therapy (CT) (Device)

control

Sham Comparator

This group will consist of twenty women with mild to moderate osteoarthritis suffering from pain.These women will perform the same strengthening exercises as intervention group and receive sham combination therapy 10 minutes for each session, 3 times per week, for 2 weeks.

干预措施: Combination therapy (CT) (Device)

结局指标

主要结局

Knee Range Of Motion

时间窗: up to four weeks

electronic goniometer it measures range of motion objectively assess ROM for extremities and digits

次要结局

  • activity of daily living(up to four weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Madonna Noshi Welson Aiad

principle investigator

Cairo University

研究点 (1)

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