ISRCTN32612072已完成未知
Physical activity programmes for community dwelling people with mild to moderate dementia (DAPA - Dementia And Physical Activity): a multi-centre, randomised controlled trial
niversity of Warwick (UK)0 个研究点目标入组 468 人开始时间: 2011年7月29日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 468
研究概览
简要总结
2015 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/25724322 2016 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/27015659 2018 results in: http://www.ncbi.nlm.nih.gov/pubmed/29769247 2018 results in: http://www.ncbi.nlm.nih.gov/pubmed/29848412 2020 results in https://pubmed.ncbi.nlm.nih.gov/32441331/ (added 12/03/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Probable dementia according to Diagnostic and Statistical Manual, Fourth Edition (DSM-IV) criteria:
- •1.1. Memory impairment with cognitive disturbance in a least one of the following domains - aphasia (language), apraxia (motor activities), agnosia (object recognition) or executive functioning (planning, sequencing, abstracting)
- •1.2. Functional decline: increasing impairment in functional ability (social, occupational, personal/self-care) related to cognitive deficits
- •2. Probable dementia of mild to moderate severity (MMSE >10)
- •3. Are able to participate in a structured exercise program:
- •3.1. Are able to sit on a chair and walk 10 feet without human assistance
- •3.2. No serious unstable illness (e.g. unstable angina)
- •4. Live in the community, either alone or with a relative, friend, or carer, or in sheltered accomodation
排除标准
- •1. People with severe dementia (MMSE <10)
- •2. People living in residential nursing homes
- •3. People with acute, unstable or terminal illness which would make participation in the exercise group impractical
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