Elucidating the Symptomatic, Explanatory and Prognostic Characteristics of GERIAtric Patients Hospitalized for COVID-19
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 700
- 试验地点
- 1
- 主要终点
- Medical history and co-morbidities
研究概览
简要总结
Statement :
- The emerging Coronavirus 2019 (COVID-19) disease, linked to the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pathogen, has been spreading worldwide since December 2019, affecting millions of people and causing hundreds of thousands of deaths, particularly among the elderly.
- The first epidemiological evidence available reveals a different expression of the disease in the elderly, associated with a high risk of delayed diagnosis and implementation of protective measures and a particularly high morbidity and mortality, especially among the frailest.
- To date, there is no effective model for predicting the severity of COVID-19 in an individual.
The investigators hypothesize that there are specificities of COVID-19 in the elderly, both etiological, diagnostic and prognostic, all of which are not yet known and understood.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalization in the Geriatric unit of the University Hospital (UH) of Angers from 15/03/2020 and until the closure of the COVID-19 geriatric sector
排除标准
- •Opposition to the use of the information collected for research purposes.
结局指标
主要结局
Medical history and co-morbidities
时间窗: baseline
listing of medical history and co-morbidities data provided by the physician and the family during hospitalization
Number of different therapeutic classes
时间窗: baseline
Number of different therapeutic classes taken per day.
Medical imaging results
时间窗: baseline
Assessment of lesion extension (percent) with medical imaging results (thoracic scan)
Diagnosis of COVID-19
时间窗: baseline
Recovery of the diagnosis method (PCR or thoracic scan)
The physical examination data, and reports of relevant investigations data provided by the physician and the family during hospitalization
时间窗: baseline
The demographic characteristics are age, sex, marital status, place of life, career, presence of un/formal assistance, ...
Electrocardiography QT Interval
时间窗: baseline
all electrocardiograms performed during hospitalization
Biological parameters
时间窗: baseline
Characterization of the COVID-19 impact on the biological parameters evaluated by blood test.
Reports of relevant investigations data provided by the physician and the family during the two-month telephone follow-up
时间窗: at the 12-month follow-up
The demographic characteristics are age, sex, marital status, place of life, career, presence of un/formal assistance, ...
Comprehensive Geriatric Assessment (CGA)
时间窗: baseline
Comprehensive geriatric assessment (CGA) is defined as a multidisciplinary diagnostic and treatment process that identifies medical, psychosocial, and functional capabilities of an older adult in order to develop a coordinated plan to maximize overall health with aging. CGA is based on the premise that a systematic evaluation of frail older persons by a team of health professionals may identify a variety of treatable health problems and lead to better health outcomes.
Length of hospitalization
时间窗: at the 12-month follow-up
Number of death from any cause
时间窗: at the 12-month follow-up
次要结局
未报告次要终点