NCT03225963Unknown不适用
Application of Proteome Profiler Antibody Arrays to Find Angiogenetic Predictors in Glioma Paitents.
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Response of bevacizumab therapy.
研究概览
简要总结
Bevacizumab has become the standard of care of recurrent glioblastoma based on promising clinical trial results with with response rates up to 50% and progression-free survival up to 9 months. In our study, we set to find the serum angiogenesis biomarkers of bevacizumab response.
详细描述
Pre-chemoradiation and post-chemoradiation peripheral blood will be obtained to see if there are some angiogenesis biomarker available for prediction of bevacizumab response later.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age older than 20 year old.
- •Glioblastoma patients who will receive chemoradiation treatment.
排除标准
- 未提供
结局指标
主要结局
Response of bevacizumab therapy.
时间窗: 3 months after bevacizumab therapy
Base on the image after bevacizumab therapy (after recurrence)
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Bevacizumab Neoadjuvant Therapy for New High-grade Gliomas in the BrainBrain GliomaNCT06747728The First Affiliated Hospital of Zhengzhou University20
已完成
早期 1 期
A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine GliomasNewly Diagnosed High-Grade GliomasDiffuse Intrinsic Pontine GliomaNCT00890786Children's Hospital Medical Center, Cincinnati27
已完成
2 期
Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant GliomaBrain CancerMalignant GliomaNCT00782756Memorial Sloan Kettering Cancer Center40
已完成
2 期
Anticancer Therapeutic Vaccination Using Telomerase-derived Universal Cancer Peptides in GlioblastomaGlioblastomaNCT04280848Centre Hospitalier Universitaire de Besancon67
招募中
不适用
Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features.Brain TumorNCT03526822Assistance Publique Hopitaux De Marseille100