ISRCTN40147207已完成未知
Bronchoalveolar lavage and biopsy findings in healthy non-smoking individuals
niversity Hospital of South Manchester NHS Foundation Trust (UK)0 个研究点目标入组 30 人开始时间: 2012年1月25日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
2012 results in https://www.ncbi.nlm.nih.gov/pubmed/22978556 (added 10/12/2019)
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Over 18 years of age
- •2. Normal lung function
- •3. Negative methacholine challenge (no bronchial hyper-reactivity)
排除标准
- •1. Recent upper respiratory infection (<4 weeks)
- •2. Pregnancy / breast feeding
- •3. Use of inhaled or oral steroids in last three months
- •4. History of drug or alcohol abuse
- •5. Chronic respiratory, cardiovascular, gastro-intestinal, haematological, neurological or psychiatric illness or chronic ill health. This includes past histroy at any age of asthma, or current symptomatic rhinitis
- •6. Symptomatic gastro-oesophageal reflux or post nasal drip, or history of chronic cough
- •7. History of auto-immunity/diabetes mellitus
- •8. Current smoker
- •9. Ex-smoker of < 6 months or >10 pack/year history
- •10. History of anaphylaxis or known allergy to lignocaine/midazolam/methacholine
研究者
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