Screening for Neurodevelopmental Disorders in Siblings of Children with Autism Diagnosed in Tertiary Centers
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 384
- 试验地点
- 1
- 主要终点
- Percentage of family participation
研究概览
简要总结
In this study, a selective and multi-stages screening for neurodevelopmental disorders (NDD) in siblings of children with a confirmed ASD is done. The main aims are to estimate the prevalence of NDD among siblings and to evaluate the feasibility and acceptability of a standardized screening procedure.
详细描述
Although NDD are frequent among siblings of children with ASD, their developmental screening is not yet sufficiently organized in routine practice. The needs and the characteristics of these siblings have yet to be better understood in order to define their developmental surveillance.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Step 1: Brothers or sisters (including stepsisters and brothers); aged between 2 and 16 years; living in Occitanie; informed and express consent of parents ; affiliated to social security.
- •Step 2: step 1 positive screening or parental concerns for child's development ; parental signed informed consent.
排除标准
- •Parents (or child) refusal to participate; adopted brother or sister. Do not speak French
结局指标
主要结局
Percentage of family participation
时间窗: 12 months
Families' participation rate and, among participants, number of children with a NDD diagnosis at the end of the screening study.
次要结局
- Sensibility, specificity, positive predictive values (PPV) and negative predictive values (NPV) of the screening procedure(12 months)
- Percentage of satisfied parents(12 months)
研究者
Véronique GONNIER
child psychiatrist
University Hospital, Montpellier