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临床试验/NCT01874912
NCT01874912已完成不适用

Human Irisin Concentration in Sarcopenia

Korea University1 个研究点 分布在 1 个国家目标入组 406 人开始时间: 2009年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
406
试验地点
1
主要终点
Serum concentration of irisin in the subjects with sarcopenia

研究概览

简要总结

Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross-sectional study, the researches investigated whether serum irisin levels are decreased in patients with sarcopenia compared with control subjects with normal muscle mass, and assessed the association between serum irisin levels and various metabolic parameters.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 20<age<80
  • apparently healthy subjects

排除标准

  • a history of cardiovascular disease
  • stage 2 hypertension
  • malignancy
  • severe renal or hepatic disease

结局指标

主要结局

Serum concentration of irisin in the subjects with sarcopenia

时间窗: 12 week

次要结局

  • The relationship of serum irisin levels with lipid profiles(12 week)
  • The relationship of serum irisin levels with skeletal muscle mass index(12 wks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

K. M. Choi

Professor

Korea University

研究点 (1)

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