Endogenous Modulation of Pain - the Tolerance to Stretch
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 19
- 试验地点
- 2
- 主要终点
- Knee extension range of motion
研究概览
简要总结
This study investigates the role of two endogenous inhibitory mechanisms; exercise-induced hypoalgesia (EIH) and a conditioning painful stimulus (CPM) on passive joint range of motion, passive resistive torque and pain sensitivity. The study is a randomized, repeated-measures cross-over study.
详细描述
The increase in range of motion following stretching is related to changes in the tolerance to stretch. The mechanistic relationships behind these changes in subject sensation are however unknown but could be related to endogenous modulation of pain.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Participants were blinded to the results of all measurements and naïve to research hypotheses.
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Eligibility for participation included the absence of any pain or other conditions that might affect the somatosensory system.
排除标准
- •Substance abuse, History of neurological or mental disabilities, Lack of ability to comply with instructions, Delayed onset of muscle soreness.
研究组 & 干预措施
Exercise-induced hypoalgesia (EIH)
Exercise-induced hypoalgesia - isometric muscle contractions of the hand flexors
干预措施: Exercise induced hypoalgesia (EIH) (Other)
Static stretch (SS)
A static stretch of the knee flexors
干预措施: Static stretch (SS) (Other)
Rest
No intervention
干预措施: Rest (Other)
Conditioning painful stimulus (CPM)
Conditioned pain modulation - cold pressure test
干预措施: Conditioned pain modulation (CPM) (Other)
结局指标
主要结局
Knee extension range of motion
时间窗: Passive knee extension range of motion was measured 10 minutes after the induction of EIH, SS, Rest and CPM
Passively induced knee extension range of motion was measured using the Biodex system 4 pro isokinetic dynamometer
次要结局
- Pressure pain thresholds(Pressure pain thresholds were measured 10 minutes after the induction of EIH, SS, Rest and CPM)
- Passive resistive torque(Passive resistive torque was measured 10 minutes after the induction of EIH, SS, Rest and CPM)