Feasibility and Efficacy of the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (U-SMART) on Mild Cognitive Impairment
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- the five-point Likert scales for satisfaction and compliance
研究概览
简要总结
The purpose of this study is to examine feasibility and efficacy of the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (U-SMART) in the elderly individuals with mild cognitive impairment (MCI).
详细描述
The Spaced Retrieval-based Memory Advancement and Rehabilitation Training (SMART) which consisted of 24 one-hour face-to-face sessions (Lee, Park et al. 2009) was developed based on the spaced retrieval training (SRT), which was effective in improving memory retention span of very mild to mild Alzheimer's disease patients. The Ubiquitous SMART (U-SMART) by transforming the current SMART to a self-administered program using an application working on IPAD was developed, and was examined its feasibility and efficacy in the elderly individuals with mild cognitive impairment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 55-90
- •Educational level above 1 year and confirmed literacy
- •Diagnosed to mild cognitive impairment by International Working Group on Mild Cognitive Impairment
- •Clinical Dementia Rating (CDR) of 0 or 0.5
排除标准
- •Diagnosed to dementia by DSM-IV
- •Evidence of delirium, confusion
- •Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
- •Evidence of severe cerebrovascular pathology
- •History of loss-of-consciousness over 1 hour due to head trauma or repetitive head trauma of mild severity
- •History of substance abuse or dependence such as alcohol
- •Presence of depressive symptoms that could influence cognitive function
- •Presence of medical comorbidities that could result in cognitive decline
- •Use of medication that could influence cognitive function seriously
结局指标
主要结局
the five-point Likert scales for satisfaction and compliance
时间窗: after 4-weeks treatment
To evaluate the feasibility of the U-SMART, the five-point Likert scales for satisfaction and compliance were applied to all participants.
Word List Memory Test of the CERAD Neuropsychological Assessment Battery
时间窗: after 4-weeks treatment
To evaluate the efficacy of the U-SMART, the Word List Memory Test (WLMT) of the CERAD neuropsychological assessment battery was applied to all participants.
次要结局
- Mini-Mental State Examination (MMSE)(after 4-weeks treatment)
研究者
Ki Woong Kim
Professor, department of neuropsychiatry
Seoul National University Bundang Hospital