Expression of B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Detection of B-catenin expression in cutanous squamous cell carcinoma and its mimickers
研究概览
简要总结
Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma from other lesions that may be similar to it
详细描述
Skin cancer is one of the most common form of cancer worldwide. Cutaneous squamous cell carcinoma is one of most common skin tumers that caused by many factors as ultra violet ,ionizing radiation and others . It was an advanced spectrum ranging from actinic keratosis to invasive and metastatic squmous cell carcinoma. Correct identification of cutaneous squamous cell carcinoma is a challenge as it has both clinically and histopathologically mimickers.
So the aim of this study is to identify the expression of B-catenin in cutaneous Squamous cell carcinoma and its mimickers.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •tissue blocks with sufficient materials Cases with sufficient data
排除标准
- •tissue blocks with insufficient and necrotic materials. Casas with insufficient data
结局指标
主要结局
Detection of B-catenin expression in cutanous squamous cell carcinoma and its mimickers
时间窗: 6 month
Detection of expression of B-catenin in cutaneous squamous cell carcinoma and its mimickers by immunohistochemical procedures using antihuman B-catenin monoclonal antibodies
次要结局
未报告次要终点
研究者
Nermin Sarwat Habib
Teaching assistant of pathology
Sohag University