NCT00015626已完成2 期
A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
National Center for Research Resources (NCRR)1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2001年4月26日最近更新:
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 试验地点
- 1
研究概览
简要总结
The goal of this study is to aggressively treat insulin resistance and its clinical manifestations when they first appear in childhood, and to prevent the subsequent progression towards impaired glucose tolerance and type-2 diabetes. In the process of this clinical trial, we will learn more about the early manifestations of insulin resistance, its treatment, and its relationship to obesity and type-2 diabetes through parallel in-vivo and in-vitro studies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 5 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obese patients (wt > 95th percentile for age, for adults increased BMI > 27) greater than 5 years of age
- •And/or presence of complications of insulin resistance such as acanthosis nigricans, dyslipidemia, elevated blood pressure, hyperandrogenism
- •Siblings and parents of patients with insulin resistance. Siblings and parents will be included only in the case of documented insulin resistance in the index subject. Insulin resistance will be documented by OGTT and/or IVGTT.
- •Family history of type II diabetes.
排除标准
- •Critically ill patients, patients will congestive heart failure, renal or liver insufficiency
- •Inability to give consent.
- •History of poor compliance with physician's recommendations
研究者
研究点 (1)
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