Epidemiology and Clinical Presentation of Human Anaplasmosis in Eastern France
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 12
- 主要终点
- Risk factor, clinical and biological markers of infection for patients with Anaplasma antibody seroconversion
研究概览
简要总结
Anaplasmosis is a tick-borne transmitted infection. Its clinical expression include fever, cytopenia and hepatitis.This infection was initially described in United States. In Europe, its epidemiology is not well known. Some isolated cases have been diagnosed in several country, were the tick Ixodes ricinus is known to transmitted another infection :the Lyme borreliosis.The purpose of our study is to look systematically for Anaplasmosis, in patient living in Eastern France, and presenting with compatible clinical symptoms using a new diagnosis tool : PCR in blood samples. So we will have new data about epidemiology in our country and the clinical symptoms that are associated with Anaplasmosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 10 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with at least one of following symptoms : fever or muscular pain or articular pain or respiratory signs or neurological signs or meningitis or erythema occurring during the three weeks after a tick bite-
- •patient with fever with at least one of following criteria : thrombocytopenia, leucopenia, hepatitis, without any other cause that can explain these abnormalities.
- •patient with tick-borne encephalitis, or primary stage Lyme borreliosis
排除标准
- •children less that 10 years
- •pregnancy
- •patients with an other diagnosis that can explain clinical symptoms or biological abnormalities
- •antibiotherapy with cyclins during the days before inclusion
结局指标
主要结局
Risk factor, clinical and biological markers of infection for patients with Anaplasma antibody seroconversion
时间窗: 6 weeks
次要结局
未报告次要终点