The Effect of Targeted Temperature Management Therapy on Pyroptosis in Patients with return of Spontaneous Circulation post Cardiac Arrest Caused by Acute Myocardial Infarction.

harran university medical faculty0 个研究点目标入组 40 人开始时间: 2021年11月18日最近更新: 2021年11月22日

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•The criteria for inclusion were a witnessed cardiac arrest, a presumed cardiac origin of the arrest, an age of 18 to 70 years, an estimated interval of 5 to 15 minutes from the patient's collapse to the first attempt at resuscitation by emergency medical personnel, and an interval of no more than 60 minutes from collapse to restoration of spontaneous circulation.

•Patients were excluded if they met any of the following criteria: esophageal temperature below 30 ° C at admission, coma before cardiac arrest due to administration of drugs that suppress the central nervous system, pregnancy, then response to verbal commands, return of spontaneous circulation, and before randomization, spontaneous Evidence of hypotension (mean arterial pressure less than 60 mm Hg), evidence of hypoxaemia (arterial oxygen saturation less than 85 percent) after return of circulation and more than 30 minutes prior to randomization, after return of spontaneous circulation and more than 15 minutes prior to randomization a fatal illness that occurred prior to arrest, factors unlikely to participate in follow-up, enrollment in another study, or a known pre-existing coagulopathy.

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harran university medical faculty