Quantifying the Trainability of Peripheral Nerve Function in Young and Older Adults.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 59
- 试验地点
- 1
- 主要终点
- Motor nerve conduction velocity (m/s)
研究概览
简要总结
The purpose of this project is to identify the effects of hand grip resistance training on nerve speed of the hand muscles and to quantify whether age plays a role in those effects. Two groups (young and older adults) underwent a 4-week resistance training intervention with nerve conduction velocity measured before and after. There were also two control groups (young and older adults) who performed the testing 4 weeks apart, but did not engage in the intervention.
详细描述
Studies have shown that nerve speed slows with advancing age. As a result, slower nerves may result in slower movement speed and can alter response time. The investigators propose that a resistance training intervention may elicit positive adaptations to the nerves. The purpose of this project is to identify the effects of hand grip resistance training on nerve speed of the hand muscles and to quantify whether age plays a role in those effects. Two groups (young and older adults) underwent a 4-week, at-home, resistance training intervention with nerve conduction velocity (m/s) measured before and after. There were also two control groups (young and older adults) who performed the testing 4 weeks apart, but did not engage in the intervention. Other outcome measures included nerve size, via ultrasound, maximal handgrip strength, and hand dexterity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy adults 18 - 100 years old.
排除标准
- •If you have been notified by a physician to refrain from exercise due to cardiovascular issues.
- •Known orthopedic or neuromuscular limitations or illness of the upper extremities.
- •Known neuromuscular disorders.
- •Individuals that are experiencing a fever (> 100.4° F) or have identified as symptomatic on the COVID-19 screening questionnaire may not participate at this time.
研究组 & 干预措施
Young Training Group
Ages 18-35. Performed 4 weeks of an at-home, hand grip resistance training intervention.
干预措施: Resistance Training (Other)
Young Control Group
Ages 18-35. Did not perform the training intervention
Older Training Group
Ages 60+. Performed 4 weeks of an at-home, hand grip resistance training intervention.
干预措施: Resistance Training (Other)
Older Control Group
Ages 60+. Did not perform the training intervention
结局指标
主要结局
Motor nerve conduction velocity (m/s)
时间窗: Before and after 4 weeks of training (or just 4 weeks, for controls)
Conduction velocity of the median nerve, via nerve stimulation, as measured through EMG at the Flexor Digitorum Superficialis muscle
次要结局
- Nerve cross-sectional area (mm^2)(Before and after 4 weeks of training (or just 4 weeks, for controls))
- Maximal strength (kg)(Before and after 4 weeks of training (or just 4 weeks, for controls))
- Hand motor dexterity (seconds)(Before and after 4 weeks of training (or just 4 weeks, for controls))