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临床试验/TCTR20201108004
TCTR20201108004已完成4 期

Clomiphene citrate plus Letrozole versus Clomiphene citrate alone for ovulation induction in infertile women with ovulatory dysfunction: a randomized controlled trial

Faculty of medicine, Siriraj Hospital0 个研究点目标入组 95 人开始时间: 2020年11月8日最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
95

研究概览

简要总结

There was no significant difference between combination CC plus letrozole and CC alone relative to their ability to induce ovulation in infertile women with chronic anovulation. Further study is needed to compare the cumulative ovulatory rate and dose-defining efficacy of these ovulation induction regimens.

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 40 Years(—)
性别
Female

入选标准

  • 1. Women age between 18 and 40 years old
  • 2. Infertile
  • 3. Chronic anovulation (cycle length more than 35 days or diagnosed with PCOS)

排除标准

  • 1. Pregnancy
  • 2. Received letrozole or clomiphene citrate within 3 month prior
  • 3. Other causes of infertile, e.g. thyrotoxicosis, hyperprolactinemia
  • 4. Uncontrolled underlying disease such as uncontrolled diabetes mellitus, uncontrolled hypertension, CA cervix
  • 5. Allergic or contraindication to letrozole or clomiphene citrate
  • 6. Husband has total motile sperm count less than 10 million

研究者

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