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临床试验/NCT04385472
NCT04385472Unknown不适用

Musculoskeletal Imaging of Runners

Royal National Orthopaedic Hospital NHS Trust1 个研究点 分布在 1 个国家目标入组 52 人开始时间: 2019年4月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
52
试验地点
1
主要终点
Change in radiographic score after marathon running

研究概览

简要总结

The investigators aimed to assess the impact of long-distance running on musculoskeletal system of runners, by doing high resolution magnetic resonance imaging analysis before and after marathon running.

详细描述

Rationale for the study: This research will examine a key modifiable risk factor for health and well- being: exercise. Regular exercise is highly recommended by healthcare professionals because the whole body benefits, including cardiorespiratory, musculoskeletal systems and mental wellbeing. Long-distance running is a popular physical activity with more than 30 million individuals running marathons each year. The increasing participation of first-time runners, including older people, has been linked to a rise in related injuries. The ideal dose of exercise is not known and overdosage affects some musculoskeletal tissues and joints more than others. Overdoing a specific amount of exercise and the presence of chronic injuries may pose a great risk on the joints, leading to serious conditions such as osteoarthritis, musculoskeletal injuries, tendinopathy. However, it is not yet clear whether a high dose of exercise such as marathon running damages the musculoskeletal system and there is a growing need for research in the area of running science to better understand this.

Aim: This research aims to do musculoskeletal imaging before and after long-distance running using 3 Tesla magnetic resonance imaging and to provide evidence on how much exercise people should undertake and how to minimise injury.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • no previous marathon participations
  • no present or previous history of hip injuries or surgeries
  • asymptomatic hip joints
  • no contradindications to hip MRI scanning

排除标准

  • pregnant or breastfeeding women
  • individuals aged <18 years
  • claustrophobia
  • history of anxiety or panic attacks
  • known hip problems

结局指标

主要结局

Change in radiographic score after marathon running

时间窗: up to 1 year

Change in self-reported hip questionnaire after marathon running

时间窗: up to 1 year

次要结局

  • Number of participants who finished the training for/and the marathon vs not finishing(up to 4 months)

研究者

发起方
Royal National Orthopaedic Hospital NHS Trust
申办方类型
Other
责任方
Principal Investigator
主要研究者

Professor Alister Hart

Professor of Orthopaedics

Royal National Orthopaedic Hospital NHS Trust

研究点 (1)

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