A randomized comparative clinical study to evaluate add on effect of Surasasidhha taila nasya with Vyoshadi vati in Allergic Rhinitis.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare add on effects of Surasasidhha taila nasya 2 drops in each nostril at morning to Vyoshadi vati 250 mg 2 tablets twice daily after meal for 21 days in Allergic rhinitis patients of age group 18 years to 50 years.
研究概览
简要总结
Allergic rhinitis is the common disease found in today’s population. In India, 20% to 30% of the population is suffering from allergic rhinitis. Changes in lifestyle, food habits and pollution contribute to the allergic conditions and lead them to chronic stages. Modern sciences treat allergic rhinitis with antihistamines and steroids given orally or nasally. But these drug have many side effects and the recurrence of disease is also noted. So there is need for the safe, effective and easily available quality drug. Allergic rhinitis is characterized by paroxysmal sneezing, nasal obstruction, watery rhinorrhoea and nasal irritation. Vyoshadi vati has been previously studied and proven to be effective in pratishyay disease. As the symptoms of allergic rhinitis are similar to those of vataj pratishyay disease described in ayurveda, Vyoshadi vati can be given to treat allergic rhinitis. Surasa i.e. Ocimum sanctum has anti allergic properties according to modern studies and is also effective in pratishyay according to ayurveda. Hence Surasasidhha tailya nasya drops given through nasal route is taken for research study. The efficacy of Vyoshadi vati given with and without Surasasidhha taila nasya is to be studied and compared in this clinical trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who are having following symptoms
- •Recurrent sneezing
- •Watery rhinorrhoea
- •Nasal obstruction.
排除标准
- •Known cases of chronic non specific infective rhinitis like hypertrophic rhinitis, atrophic rhinitis, rhinitis sicca, rhinitis caseosa, malignant granuloma.
- •Known cases of chronic specific infective rhinitis like syphilis, leprosy, T.B., lupus vulgaris, rhinosporidiosis, rhinoscleroma, fungal infections and leishmaniasis.
- •Patients with known case of systemic illnesses like hypertension, diabetes mellitus, HIV and HbSAg.
- •Patients with DNS, nasal polyps, tumors, malignancy of any kind.
- •Pregnant women.
结局指标
主要结局
To compare add on effects of Surasasidhha taila nasya 2 drops in each nostril at morning to Vyoshadi vati 250 mg 2 tablets twice daily after meal for 21 days in Allergic rhinitis patients of age group 18 years to 50 years.
时间窗: 21 days with follow up on 8th, 15th, 22nd day and 1 month after completion of the treatment.
次要结局
- To observe the adverse effects of the drugs if any.(21 days with follow up on 8th, 15th, 22nd day and 1 month after completion of the treatment.)