临床试验/NCT05875649

NCT05875649尚未招募不适用

A Multicenter Prospective Cohort Study Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction Failure

Nanfang Hospital, Southern Medical University1 个研究点分布在 1 个国家目标入组 137 人开始时间: 2023年7月2日最近更新: 2023年7月5日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Nanfang Hospital, Southern Medical University
入组人数: 137
试验地点: 1
主要终点: Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction failure

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Most of patients with acute myeloid leukemia achieved complete remission (CR) after primary induction chemotherapy, there were 20-30% patients without CR after first-induction. It was uncertain how to treat these patients. It was investigated in our study that these patients were re-induced with CLAG Regimen. The CR ratio, overall survival (OS) and relapsed-free survival (RFS) was statistically analysed in these patients.

研究设计

研究类型: Observational
观察模型: Case Only
时间视角: Prospective

入排标准

年龄范围: 14 Years 至 65 Years（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Acute myeloid leukemia patients with first-induction failure

排除标准

•Acute myeloid leukemia patients with serious infection and organ dysfunction.

结局指标

主要结局

Study of CLAG Regimen in Acute Myeloid Leukemia Patients With First-induction failure

时间窗: 6 months

CLAG Regimen improves CR rate in acute myeloid leukemia patients with first-induction failure

次要结局

未报告次要终点

研究者

发起方

Nanfang Hospital, Southern Medical University

申办方类型

Other

责任方

Sponsor

研究点 (1)

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