DRKS00024575招募中未知
Strength training for the treatment of Cushing's associated myopathy: a randomised study - CAESAR
Medizinische Klinik und Poliklinik IV, LMU Klinikum München0 个研究点目标入组 42 人开始时间: 2021年4月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 42
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 60 Years（—）
- 性别
- All
入选标准
- •Cushing's syndrome:
- •- path. Dexamethasone inhibition test
- •- path. 23 o'clock salivary cortisol level
- •- path. 24h-collection urine cortisol (>2.0 UNL)
- •- planned surgery
- •- Confirmed subtype: adrenal, pituitary or ectopic
- •Cushing's syndrome in long-term remission:
- •- Successfully treated Cushing's syndrome
- •- Persisting functional impairment
- •Metabolic syndrome:
- •- Functional impairment
- •- Exclusion of hypercortisolism
- •- Central obesity and at least 2 of the following criteria: Serum triglycerides < 150 mg/dl; reduced serum HDL cholesterol < 50 mg/dl; art. Hypertension (> 130/85mmHg); elevated fasting blood glucose (> 100mg/dl) or type II diabetes - or drug treatment of any of these symptoms
排除标准
- •- Age under 18 years or over 60 years
- •- Contraindication to surgery
- •- Existing pregnancy
- •- Chronic general illness
- •- Alcohol or drug abuse
- •- Physical limitation to participate in the exercise program
- •- Participation in another interventional clinical trial
- •- Life expectancy of less than one year
- •- Myocardial infarction within the past 3 months
- •- Cardiopulmonary instability or ischemia signs during exercise testing
- •- Cytostatic therapy
研究者
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