A comparative study of effect of intravenous magnesium sulphate versus lignocaine in reduction of succinylcholine induced fasciculations and postoperative myalgia in patients undergoing elective surgery
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- To valuate the occurrence of succinylcholine induced fasciculation and post
研究概览
简要总结
This study is a Randomised , Comparative ,parallel group ,Double Blind Study to evaluate the occurrence of succinylcholine induced fasciculation and post
operative myalgia after pre-treatment with IV Mgso4 30mg/kg and and IV preservatives
free 2% lignocaine 1.5 mg/kg in total of 94 patients undergoing elective surgery .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anesthesiologists (ASA) physical status grade I and II 2.Modified Mallampati Airway (MMA) (Samsoon Young) class I And II
- •Scheduled for elective surgeries under general anesthesia.
- •Patient who are willing to give consent.Â.
排除标准
- •Patients with history of significant systemic disorders (cardiovascular, respiratory, central nervous system or renal system)
- •Pre-existing musculoskeletal disorders.
- •Hypermagnesemia with a diagnosed condition or with altered serum values, altered liver function tests.
- •4.Beta-adrenergic or calcium channel blocker usage
- •Known hypersensitivity and contraindications to study drugs in allergic history family history.
结局指标
主要结局
To valuate the occurrence of succinylcholine induced fasciculation and post
时间窗: From General anaesthesia induction to 24 hour postoperative period
operative myalgia after pre-treatment with IV Mgso4 30mg/kg and IV preservatives
时间窗: From General anaesthesia induction to 24 hour postoperative period
free 2% lignocaine 1.5mg/kg
时间窗: From General anaesthesia induction to 24 hour postoperative period
次要结局
- 1. To compare the severity of succinylcholine induced fasciculation and postoperative(myalgia.)
研究者
Dr Nidhishree V
ESIC Medical College PGIMSR