Breathing and anxiety: Understanding the effect of exercise on the possible miscommunication between brain and body in individuals with moderate levels of anxiety

niversity of Otago0 个研究点目标入组 125 人开始时间: 2020年11月30日最近更新: 2024年5月27日

适应症

试验速览

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•Male or female aged between 18 and 45 years
•Ability to provide written and informed consent
•Ability to adhere to the study protocol
•Spielberger trait anxiety score of greater than or equal to 40 (for moderate anxiety participants) OR less than or equal to 30 (for cross-sectional low anxiety controls)
•Engaged in minimal organised sport or fitness activity (<1 per week for the last 6 months or more)

•Evidence of severe acute or chronic medical disorders, including a neurological disorder, current or past history of a severe brain injury or severe respiratory disorder e.g. severe asthma, chronic obstructive pulmonary disease etc.
•Past or current diagnoses of schizophrenia, bipolar disorder, drug addiction or psychosis
•Colour blindness
•Female patients who are pregnant or breastfeeding
•Current significant suicidal ideation
•Participants must be free of recreational drug and alcohol use at the time of testing
•Presence of implanted cardiac pacemakers, hearing aids, insulin pumps or neurostimulators; intracranial metal clips; or metallic bodies in the eye (MRI safety)
•Significant levels of smoking or vaping (more than once per week)
•Any regular medication (except the oral contraceptive pill for women)
•Contraindication to engaging in a progressive exercise program, as determined from a validated health-screening questionnaire (PAR-Q+).

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