Clinic Features and Long-term Outcome of Different Subgroups of Brochopulmonary Dysplasia in Preterm Infants
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
This study described the perinatal high-risk factors and clinical manifestations of the children, and compared the high-risk factors, clinical manifestations and prognosis of BPD among different clinical subtypes by comparison between groups. BPD grading was performed using the 2018 grading standard to compare the distribution of I/II/III BPD among different groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Premature infants born at <32 weeks of gestational age;
- •hospitalization time ≥ 14 days;
- •The clinical medical records are complete
排除标准
- •• 1) Children with congenital heart, lung malformation and definite chromosomal diseases; 2) children gave up treatment halfway; 3) corrected gestational age 36 weeks before death, the cause of death was confirmed as factors other than respiratory system.
结局指标
主要结局
Mortality
时间窗: up to 12 months after birth
Different subtype of BPD infants against the total BPD infants in corresponding group
Duration of first hospital stay
时间窗: up to 12 months after birth
days between admission and first discharge
Days with oxygen supplement
时间窗: up to 12 months after birth
days during which the infants were given oxygen
Days of Mechanical Ventilation
时间窗: up to 12 months after birth
days during which the infants were given mechanical ventilation
Serious respiratory mobidities
时间窗: up to 18 months after birth
occurence of at least one of the following: tracheostomy, continued hospitalization for respiratory reasons at or beyond 50weeks PMA; continued oxygen supplement or respiratory support beyond 12months after birth; readmission for respiratory reasons.
次要结局
- head circumference(up to 18months after birth)
- weight(up to 18months after birth)
- length(up to 18months after birth)
研究者
Wang Jianhui
Attending doctor
Children's Hospital of Chongqing Medical University