Oxycodone Concentration in the Blood After Oral Premedication
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Oxycodone concentration in the blood after oral premedication
研究概览
简要总结
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy testpersons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg
详细描述
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy test-persons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg 20 female patients between 30 and 60 years will be included after informed consent. They will have day-surgery. The patients will receive 5 mg oxycodone if weighing less than 60 kg and 10 mg if weighing over 60 kg. Serum samples will be taken 1, 2,3,4, and 5 hours after medication intake and serum concentrations will be analyzed
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Females <100kg, non-opioid tolerant, day surgery and informed consent
排除标准
- •In complying to inclusion criterias
研究组 & 干预措施
day surgery patients
20 patients female 30-60 years of age
干预措施: Oxycodone (Drug)
结局指标
主要结局
Oxycodone concentration in the blood after oral premedication
时间窗: 2 days
Concentration study
Oxycodone concentrations and pain after oral premedication
时间窗: 7 day
Visual analoge Scale
次要结局
未报告次要终点
研究者
Bengt Nellgard
Associate professor
Sahlgrenska University Hospital, Sweden