A Prospective, Multicenter,Registry Study of Aortic Valve Stenosis in Zhejiang Elderly
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1
- 试验地点
- 1
- 主要终点
- All-cause mortality,disabling strokes and Surgical or transcatheter aortic valve replacement
研究概览
简要总结
Aortic valve stenosis (AVS) is becoming more and more frequent with the aging, which has brought a heavy burden to the world. However, the prevalence and prognosis of valvular heart disease are not so clear, especially in the developing countries such as China etc. Because of the slow and progressive nature of AVS, symptoms might not be too severe to be diagnosed on time. Our retrospective survey (Int J Cardiol. 2016 Nov 25) indicated that severe aortic valve stenosis are very common in China. Hence, we design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese elderly patients with aortic valve stenosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 60 years old meet the following condition moderate or above aortic stenosis as defined by echocardiography: Aortic stenosis, moderate or above, or valve area≤1.5cm2, or maximal jet velocity ≥3.0m/sec, or mean pressure gradient≥20mmHg
排除标准
- •Patients cannot be followed up for any reasons.
- •Patients in critical condition may be die in one year.
- •Patients have been enrolled in this study.
结局指标
主要结局
All-cause mortality,disabling strokes and Surgical or transcatheter aortic valve replacement
时间窗: one year
time from enrolled to first occurrence of any of the components of the composite outcome
次要结局
- Surgical or transcatheter aortic valve replacement(one year)
- Hospitalization for heart failure(one year)
- Cardiovascular death(one year)
研究者
Jian'an Wang,MD,PhD
President of Second Affiliated Hospital, School of Medicine, Zhejiang University & Chief of Cardiology
Second Affiliated Hospital, School of Medicine, Zhejiang University