Effect of Medium Chain Triglyceride Consumption on Appetite
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Food intake
研究概览
简要总结
The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 19 Years 至 50 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Weight stable (<10 lb over previous 3 months)
- •Overweight (body mass index 25-29.9)
排除标准
- •Excessive caffeine users
- •Severe health conditions
- •Allergy to food products/ingredients in the study
- •Taking medications known to affect energy expenditure or gastrointestinal function
研究组 & 干预措施
MCT
MCT oil (20 g) was included in the test breakfast
干预措施: Test breakfast (Dietary Supplement)
LCT
Corn oil (20 g) was included in the test breakfast
干预措施: Test breakfast (Dietary Supplement)
结局指标
主要结局
Food intake
时间窗: up to 3 hours
Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)
次要结局
- Ghrelin(3 hours)
- Peptide YY(3 hours)
- Glucagon-like peptide 1(3 hours)
- Insulin(3 hours)
- Triglycerides(3 hours)
- Leptin(3 hours)
研究者
Marie-Pierre St-Onge
Research Associate
St. Luke's-Roosevelt Hospital Center