临床试验/NCT02908438

NCT02908438Unknown1 期

Gonadotrophin Releasing Hormone Agonist Addition for Luteal Support in In-vitro Fertilization and Embryo Transfer Cycles

Northwest Women's and Children's Hospital, Xi'an, Shaanxi0 个研究点目标入组 400 人开始时间: 2016年9月最近更新: 2016年9月21日

适应症

干预措施

试验速览

阶段: 1 期
发起方
入组人数: 400
主要终点: pregnancy rate

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者记录与标识符相似试验

研究概览

简要总结

The study was designed to investigate the effect of luteal-phase administration of gonadotrophin releasing hormone agonist(GnRHa) on pregnancy outcomes in in-vitro fertilization-embryo transfer.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 37 Years（Adult）
性别: Female
接受健康志愿者: 否

入选标准

•Age < 37 years;
•One or more high quality embryos have been got in IVF/ICSI treatment;
•To transfer at lest 2 fresh embryos;
•Uterine endometrial thickness ≥ 7mm;
•Patients have signed informed consents.

排除标准

•≥3 IVF/ICSI/FET cycles and no pregnancy;
•Polycystic ovary syndrome(PCOS);
•uterine malformation;
•endometriosis
•patients with a history of recurrent pregnancy loss.

研究组 & 干预措施

GnRHa group

Experimental

Intervention: additional GnRHa for routine LPS GnRHa group receive three injections of GnRHa(Decapeptyl) ,0.1 mg s.c. on the day of ET, and D3 and D6 after ET in addition to routine LPS.

干预措施: Gonadotrophin releasing hormone agonist(GnRHa) (Drug)

结局指标

主要结局

pregnancy rate

时间窗: up to 12 months

次要结局

未报告次要终点

研究者

发起方

Northwest Women's and Children's Hospital, Xi'an, Shaanxi

申办方类型

Other

责任方

Sponsor

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