NCT05095155已完成不适用
Preventive and Personalized Medicine (2021-2023)
Asfendiyarov Kazakh National Medical University1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2022年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Associated with B-cell lymphoma and B-cell acute lymphoblastic leukemia
研究概览
简要总结
To search for a genetic marker of B-cell leukemias and lymphomas in children of Kazakh nationality, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with B-cell leukemias and lymphomas in children of Kazakh nationality and normal control will be performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ethnicity - Kazakhs in at least three generations
- •active disease or a history of B-line ALL or B-NHL, established on the basis of morphological, cytochemical, immunophenotypic or immunohistochemical research methods with confirmation of the fact of the disease in medical documentation
- •Signed voluntary informed consent of the legal representative to participate in the project
排除标准
- •Children suffering from other types of malignant neoplasms
- •Children with B-linear leukemia and lymphomas with concomitant specified genetic and chromosomal diseases
- •Children of non-Kazakh nationality
- •Absence of signed informed consent or informed refusal of the legal representative to participate in the study before starting therapy
结局指标
主要结局
Associated with B-cell lymphoma and B-cell acute lymphoblastic leukemia
时间窗: 1 year
Genotype frequency of SNP in the study genes of participants and control participants.
次要结局
未报告次要终点
研究者
Ildar Fakhradiyev
Head of the Laboratory of Experimental Medicine
Asfendiyarov Kazakh National Medical University
研究点 (1)
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