Postoperative Pain After Endodontic Irrigation Using 1.3% Versus 5.25% Sodium Hypochlorite
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 308
- 主要终点
- Postoperative pain using a pain-measuring scale
研究概览
简要总结
The aim of this prospective, randomized, clinical trial was to evaluate the effect of 1.3% sodium hypochlorite (NaOCl) concentration versus 5.25% NaOCl concentration on post-operative pain and medication intake in adult patients with pulp necrosis in mandibular molars.
详细描述
The aim of this prospective, randomized, clinical trial was to evaluate the effect of 1.3% sodium hypochlorite (NaOCl) concentration versus 5.25% NaOCl concentration on post-operative pain and medication intake in adult patients with pulp necrosis in mandibular molars. Medical and dental history was obtained from all participants in this trial and clinical and radiographic evaluation for teeth was recorded. Participants with pulp necrosis with or without apical periodontitis were included. After access cavity preparation, participants were randomly assigned to one of the following groups: experimental group (irrigation using 1.3% NaOCl) or control group (irrigation using 5.25% NaOCl ). Two-visit root canal treatment was performed with a week interval in between visits. Each patient received a 7-day diary to record postoperative pain and rescue medication intake. Post-operative pain was measured at the following time points: immediately , 3, 24, 48 hours and 7 days after the first visit and postobturation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 25-45 year old.
- •Medically free.
- •Non-vital mandibular teeth (first or second molar) with or without apical periodontitis
- •No sex predilection
排除标准
- •Pregnant females.
- •History of allergy to any medication used in the study.
- •Preoperative premedication 12 hours before procedure.
- •Acute abscess cases.
- •Badly-decayed crown.
- •Retreatment cases
研究组 & 干预措施
1.3% NaOCl
Root canal irrigation done using 1.3% NaOCl.
干预措施: 1.3% NaOCl (Other)
5.25% NaOCl
Root canal irrigation done using 5.25% NaOCl.
干预措施: 5.25% NaOCl (Other)
结局指标
主要结局
Postoperative pain using a pain-measuring scale
时间窗: immediately after obturation
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured immediately after obturation.
Postoperative pain using a pain-measuring scale
时间窗: immediately after treatment
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured immediately after the first visit
Postoperative pain using a pain-measuring scale
时间窗: 3 hours
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured 3 hours after the first visit
Postoperative pain using a pain-measuring scale
时间窗: 24 hours
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured 24 hours after the first visit
Postoperative pain using a pain-measuring scale
时间窗: 48 hours
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured 48 hours after the first visit
Postoperative pain using a pain-measuring scale
时间窗: 7 days
Postoperative pain is measured using the Numerical Rating Scale (NRS) which is an 11-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured 7 days after the first visit
次要结局
- Sham medication intake incidence(7 days)
- Analgesic medication intake incidence(7 days)