Effect of Glycogen Replenishment on Time Trial Performance Following a Glycogen Lowering Exercise
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- 20 km time trial
研究概览
简要总结
Fifteen endurance-trained male/female will be randomly assigned to do four exercise and nutrition trials involving ingestion of four different concentrations of sweet corn derived starch (food component) in water (0, 1, 1.5 and 2 g. kg-1. h-1). Each trial will be separated by at least one week. During these four experimental trials athletes will be subjected to a glycogen-lowering cycling exercise protocol followed by a 4-h post-exercise recovery period (2h feeding then 2 hours of rest). At the end of 4-h period they will do a 20 kilometre time trial test on a stationary bike in a laboratory condition to measure the effect of different glycogen repletion rates on exercise performance.
详细描述
Post-exercise glycogen synthesis rate is an important factor in determining the time needed to recover. Glycogen synthesis is affected not only by the extent of glycogen depletion but also in a more direct manner by the type, duration, and intensity of the preceding exercise because these will differentially influence the acute enzymatic changes as well as recovery from the acute changes that are induced by strenuous exercise. To optimize glycogen synthesis rates, adequate amounts of carbohydrate should be ingested. It has been suggested initially that a carbohydrate intake of 0.35 g·kg body wt-1 ·h-1 , provided at 2-h intervals, maximized muscle glycogen synthesis. Others observed no differences in glycogen storage rates after subjects ingested 0.75 or 1.5 g carbohydrate·kg-1 · h-1 provided at 2-h intervals. In a follow-up study, it was reported that an intake of >0.5 g·kg-1 · h-1 is necessary to maximize post-exercise glycogen synthesis if supplements are administered at 2-h intervals. Higher glycogen synthesis rates have been reported in studies in which carbohydrates were ingested more frequently and at higher ingestion rates than in previous studies. Other efforts to increase glycogen synthesis rates by changing the form of administration (ie, as a solution, as a solid, or intravenously) have been unsuccessful. While the above range of intake rates has been suggested to maximize muscle glycogen resynthesis post-exercise, the required dosage with sweet corn derived high glycemic starch and its effect on a subsequent time trial exercise is currently unknown. So, investigators objective in this experiment is to find out optimal sweet corn derived recovery ingestion dose by using a glycogen lowering exercise protocol, followed by glycogen repletion via ingestion and a subsequent 20 km time trial cycling performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- Single (Participant)
盲法说明
Flavoured water placebo drink with no energy or carbohydrate drinks in opaque bottles to keep participant blinded
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •are a healthy male or female endurance athlete of 18- 40 years of age
- •have ≥2 y endurance training experience; training for ˃1 h/day
排除标准
- •Have symptoms or take medication for respiratory disease
- •Have symptoms or take medication for cardiovascular disease
- •Have symptoms or take medication for metabolic disease
- •Have symptoms or take mediation for neuromuscular disease
- •Use heart rate or blood pressure medications
- •Use any medications with side effects of dizziness, lack of motor control, or slowed reaction time
- •Have any cardiovascular or neuromuscular limitations to exercise
- •Are pregnant or find out that you are pregnant during experiment
研究组 & 干预措施
Placebo
Placebo flavored drink similar to treatments but with no energy will be ingested post glycogen lowering exercise, followed by a 20 km time trial intervention
干预措施: 20 km time trial performance (Behavioral)
Placebo
Placebo flavored drink similar to treatments but with no energy will be ingested post glycogen lowering exercise, followed by a 20 km time trial intervention
干预措施: Glycogen lowering exercise (Behavioral)
Carbohydrate drinks
Sweet corn derived starch mixed in water at three different concentrations (6%, 12% and 18%) will be ingested post glycogen lowering exercise, followed by a 20 km time trial intervention
干预措施: 20 km time trial performance (Behavioral)
Carbohydrate drinks
Sweet corn derived starch mixed in water at three different concentrations (6%, 12% and 18%) will be ingested post glycogen lowering exercise, followed by a 20 km time trial intervention
干预措施: Glycogen lowering exercise (Behavioral)
结局指标
主要结局
20 km time trial
时间窗: 40 minutes
participants will ride for 20 km on a stationary bike and time to finish will be measured
次要结局
- VO2(2 hours)
- Blood glucose(2 hours)
- VCO2(2 hours)
- Serum insulin(2 hours)
- Blood lactate(2 hours)
研究者
Peter Lemon
Professor
Western University, Canada
