NCT00618332已完成不适用
Does the Response to a Nasal Decongestant Test Predict the Outcome to Treatment of Seasonal Allergic Rhinitis With Nasonex?
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Global Assessment
研究概览
简要总结
We hypothesize that those patients with purely seasonal allergic rhinitis will decongest better than those subjects with another cause contributing to their symptoms. These latter patients will not improve as well on an intranasal steroid as those who decongest well, potentially explaining the 60% response rate in prior studies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
1
Active Comparator
2 weeks of treatment
干预措施: mometasone furoate nasal spray (Drug)
2
Placebo Comparator
2 weeks of treatment
干预措施: placebo (Drug)
结局指标
主要结局
Global Assessment
时间窗: at week 2
Global Assessment: 3=significantly improved, 2=moderately improved, 1=mildly improved, 0=no change, -1=mildly worse, -2=moderately worse, and -3=significantly worse
次要结局
- Changes in RQLQ: Overall(Baseline and 2 weeks)
- Changes in RQLQ: Activity(Baseline and 2 weeks)
- Changes in RQLQ: Sleep(Baseline and 2 weeks)
- Changes in RQLQ: Non-Nasal/Eye(Baseline and 2 weeks)
- Changes in RQLQ: Practical(Baseline and 2 weeks)
- Changes in RQLQ: Nasal(Baseline and 2 weeks)
- Changes in RQLQ: Emotional(Baseline and 2 weeks)
- Changes in RQLQ: Eye(Baseline and 2 weeks)
研究者
研究点 (1)
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