NCT02443233已完成不适用
Evaluation of Paternal, Maternal and Obstetric Factors Leading to the Hepatitis B Immunization Failure in Hong Kong
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 750
- 试验地点
- 1
- 主要终点
- The effect of high maternal viral load on immunoprophylaxis failure, using 10^6 copies/ml as cut-off
研究概览
简要总结
Globally, hepatitis B virus (HBV) infection is the most common form of chronic hepatitis. There are still a lot of uncertainties on how infants acquired HBV leading to the development of chronic HBV infection despite active and passive immunoprophylaxis. The investigators would like to carry out a prospective study to answer the following questions:
- the paternal, maternal and obstetric factors leading to immunoprophylaxis failure
- the prevalence of immunoprophylaxis failure in Hong Kong
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All women age ≥ 18 years
- •Maternal or paternal hepatitis B carrier
排除标准
- •Couples will be excluded if female partners of paternal hepatitis B carrier were occult carrier
- •Plan to deliver in other units
结局指标
主要结局
The effect of high maternal viral load on immunoprophylaxis failure, using 10^6 copies/ml as cut-off
时间窗: Infants' blood for HbsAg at 9-12 months old
次要结局
未报告次要终点
研究者
研究点 (1)
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