NCT04899817Unknown4 期
Efficacy and Safety of Granisteron Versus Metoclopramide as Prophylaxis Antiemetic in Laparoscopic Cholecystectomy
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Postoperative nausea and vomitting
研究概览
简要总结
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
详细描述
Post operative nausea and vomitting is Avery common complication of laparoscopic surgery in that study we will compare between granisteron and metoclopramide as aprophlaxis against post operative nausea and vomitting
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •both sexes Age between 18 and 60 years ASA1 2 3 Lap cholecystectomy under general anesthesia
排除标准
- •patients refusal Pregnancy and breastfeeding Hepatic or renal disease ASA4 5 Allergy to the drug
研究组 & 干预措施
Group G
Active Comparator
will receive granisteron 1mg after induction of general anesthesia
干预措施: Granisetron (Drug)
Group C
Placebo Comparator
Will receive metoclopramide 10 mg after induction of general anesthesia
干预措施: Granisetron (Drug)
结局指标
主要结局
Postoperative nausea and vomitting
时间窗: Every 2 hours for 12 hours
Number of attacks of nausea and vomitting
次要结局
未报告次要终点
研究者
Lyali Salah Dardeer
Assistant lecturer
Assiut University
研究点 (1)
Loading locations...
相似试验
已完成
3 期
A Comparison of Granisetron and Metoclopramide in the treatment of nausea and vomiting in patients with migraine headachemigraine headache.MigraineIRCT201112038292N1Tehran University of Medical Sciences150
已完成
4 期
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine SurgeryPostoperative Nausea and VomitingScoliosisNCT06540885University of Malaya74
Unknown
早期 1 期
Granisetron Versus Metoclopramide Effects on Gastric Volume by Sonographic Assessment on Patients Undergoing Caesarean Section.Aspiration VomitusNCT04290026Assiut University90
已完成
3 期
A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIA1mg Vs 3 mg of GranisetronNCT04918862Cairo University210
已完成
3 期
Efficacy and Safety of GTR in Comparison to Copaxone®Multiple SclerosisNCT01489254Synthon BV794