CTIS2024-510885-17-01进行中（未招募）1 期
Defining the Glucagon Unit: Investigating the Impact on Energy Expenditure and Glucose Level Deviation in healthy volunteers - VPP-EM-2022/1-0001
Pauls Stradins Clinical University Hospital0 个研究点目标入组 10 人开始时间: 2024年4月16日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
- 性别
- Male
入选标准
- •Age 18 - 40 years., Male sex, BMI 25 - 34.9., Signed informed consent
排除标准
- •Not signed informed consent, Abnormal laboratory results: ? TSH < 0,4 or > 4,0 mIU/L ? ALAT > 40 U/L ? CKD (GFR < 90 ml/min/m2) ? Abnormal fasting glucose (=6.1 mmol/L) ? abnormal HbA1c (=5.7%) ? Other significant deviations according to research team views, Diabetes mellitus (any type)., Current use of any anti-diabetic drugs (for any indication)., Any other medical condition or treatment that, in the opinion of the investigator, would interfere with the study objectives, conduct, or interpretation of results., Inability to tolerate calorimeter canopy., Participants who have received any investigational product or medication within 180 days prior to screening., Participants who have donated blood or plasma within 30 days prior to screening., Participants who have a known allergy or intolerance to any of the study medications or their components., Inability to comply with study requirements, BMI > 35 kg/m2 and < 25 kg/m2, History of gastrointestinal disorders, surgery or other medical conditions that could affect nutrient absorption and/or predispose a subject to side effects of GLP-RA (chronic pancreatitis, dysmotility, rapidly growing thyroid nodules etc)
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