The Comparison of the Effects of Low and Medium Flow Anesthesia on Haemodynamics, Arrhytmia Risk and Cerebral Oxygenation in Laparoscopic Cholecystomy Cases
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 76
- 试验地点
- 1
- 主要终点
- the effects of low-flow anesthesia on hemodynamic stability
研究概览
简要总结
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
详细描述
The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 17 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •being ASA1-2 status
- •between the ages of 18-70
- •who are planned for laparoscopic cholecystectomy
排除标准
- •Patients who refuse to give informed consent
- •Pregnant and breastfeeding patients
- •Morbidly obese patients (Body mass index over 40)
- •Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
- •Patients using drugs known to prolong myocardial repolarization
- •inability to increase SPO2 above 95 despite necessary intervention
研究组 & 干预措施
low flow anesthesia
Maintenance of anaesthesia with low-flow anaesthesia
干预措施: low- medium flow anesthetic machine (Device)
Medium Flow Anesthesia
Maintenance of anaesthesia with medium-flow anaesthesia
干预措施: low- medium flow anesthetic machine (Device)
Medium Flow Anesthesia
Maintenance of anaesthesia with medium-flow anaesthesia
干预措施: Sevoflurane (Volatile Anesthetic) (Device)
low flow anesthesia
Maintenance of anaesthesia with low-flow anaesthesia
干预措施: Sevoflurane (Volatile Anesthetic) (Device)
结局指标
主要结局
the effects of low-flow anesthesia on hemodynamic stability
时间窗: in 2 months
The primary objective was to detect the adverse effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk
次要结局
- the cerebral oxygenation(in 2 months)
研究者
Senay Goksu
specialist
Umraniye Education and Research Hospital