A Home Transfusion Program for Patients With Advanced Hematologic Malignancies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Enrollment Rate
研究概览
简要总结
The purpose of the research is to assess the feasibility and acceptability of a home blood transfusion program for patients with hematologic malignancies who need blood transfusions
详细描述
This feasibility study will be used to assess the feasibility and acceptability of a hospice-embedded home transfusion program to patients with hematologic malignancies. All enrolled subjects will be patients cared for at Dana Farber Cancer Institute.
This study is a single-arm study of 10 patients with advanced hematologic malignancies who have a limited life-expectancy of six months or fewer and are hospice eligible.
10 Caregivers of enrolled patients will also be invited to participate if interested.
This research study involves completing questionnaires, a brief interview, blood draws, and blood transfusions when needed.
Participants will be in the research study for up to six months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with advanced hematologic malignancies:
- •Diagnosis of a hematologic malignancy
- •Age ≥ 18 years
- •Receipt of primary oncologic care at DFCI (at least 2 outpatient visits in 12 months prior to enrollment)
- •Has received at least one red blood cell (RBC) or platelet transfusion since blood cancer diagnosis in the clinic or hospital setting without a serious adverse transfusion reaction
- •Physician-estimated prognosis of six months or less
- •Has an adult informal caregiver that lives in the same residence
- •Patient resides within catchment served by Care Dimensions Hospice
- •Caregivers:
- •Identified informal caregiver of enrolled patient with hematologic malignancy
- •Age ≥ 18 years
排除标准
- •Age < 18 years
- •Does not have an identified adult informal caregiver who lives in the same residence
- •History of previous serious adverse transfusion reaction
- •Presence of decompensated congestive heart failure
- •Caregiver
- •Age < 18 years
- •Our study will exclude members of the following special populations:
- •Adults unable to consent
- •Individuals who are not yet adults (infants, children, teenagers)
- •Pregnant women
- •Prisoners
结局指标
主要结局
Enrollment Rate
时间窗: 6 months
Number of patients consented to the study divided by eligible patients approached by the study team
Completion of Home Transfusions and Patient-Reported Data
时间窗: 6 months
Proportion of completed home transfusions among enrolled patients who meet transfusion criteria, and proportion of enrolled patients who complete patient-reported data collection
次要结局
- Satisfaction Rate(3 Weeks)
- Disenrollment Rate(6 months)
研究者
Oreofe Odejide, MD
Principal Investigator
Dana-Farber Cancer Institute