NCT01781169已完成不适用
Health Effect of Oral Vitamin D Supplementation on Obese Chinese Males
Shenzhen Center for Chronic Disease Control1 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2011年4月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Plasma 25-hydroxy Vitamin D (25(OH)D) Level (Nmol/L)
研究概览
简要总结
Hypothesis: Oral Supplementation of Vitamin D can Reduce Hypersecretion of Parathyroid Hormone and Insulin Resistance in Obese Chinese Males.
Protocol: Weekly oral supplementation of 50,000 IU vitamin D (cholecalciferol) or eight weeks to the obese males compared with the normal-weight males. Index measures were conducted at baseline and endpoint.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 23 Years 至 66 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •body mass index (BMI) ≥ 28kg/m2 or 18.5 ≤ BMI < 24 (kg/m2)
- •non vegetarian Han Chinese and did not smoke, drink, nor take vitamin D supplements for > 2 y
- •fasting serum glucose < 7.0 mmol/L
- •serum glucose of 2 hr after 75 g oral glucose loading < 11.1 mmol/L
- •normal functioning of liver and kidney evaluated by alkaline phosphatase, aspartate aminotransferase, creatinine, and uric acid
排除标准
- •not match the above inclusion criteria
- •diagnosed as having any organic diseases were excluded
结局指标
主要结局
Plasma 25-hydroxy Vitamin D (25(OH)D) Level (Nmol/L)
时间窗: Endpoint and baseline of the 8 weeks' trial
次要结局
未报告次要终点
研究者
Zhou Ji-Chang
Vice Dean of Molecular Biology Lab
Shenzhen Center for Chronic Disease Control
研究点 (1)
Loading locations...
相似试验
已完成
早期 1 期
Vitamin D Supplementation and PTH Response Among Malaysian AdultsHealthyNCT05281107International Medical University106
已完成
2 期
Effect of Vitamin D Treatment in Primary HyperparathyroidismVitamin D DeficiencyPrimary HyperparathyroidismHypercalcemiaNCT00674154University of Aarhus46
已完成
3 期
Effect of vitamin D supplementation in the treatment of polycystic ovary syndromeIRCT20170513033941N53Arak University of Medical Sciences40
招募中
不适用
Evaluation of impact of vitamin-D on circulating thyroid autoantibodies in autoimmune primary hypothyroidismCTRI/2015/04/005713Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital200
已完成
4 期
Effect of Escalating Oral Vitamin D Replacement on HOMA-IR in Vitamin D Deficient Type 2 DiabeticsVitamin D DeficiencyInsulin ResistanceDiabetes Mellitus, Type 2NCT04183257King Edward Medical University106