NCT04837183终止不适用
Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- Mayo Clinic
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change in LF/HF ratio
研究概览
简要总结
This study is being done to determine whether there is an increase in sympathetic nerve activity before the onset of ventricular arrhythmias or irregular heartbeat rhythm. In addition, this study is looking at the relationship between sympathetic nerve activity and how patients with ventricular arrhythmias respond to catheter ablation treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have non-sustained or sustained VA (VA ≥ 30s or receiving appropriate ICD therapies) are presented to the clinic or admitted to the hospital within 7 days of episodes.
- •The causes of VA are associated with structural heart diseases including ischemic or nonischemic cardiomyopathy (idiopathic cardiomyopathy, hypertrophic cardiomyopathy, cardiac sarcoidosis or amyloidosis, and arrhythmogentic right ventricular dysplasia).
- •Subjects are 18 years of age and older.
排除标准
- •Female patients who is pregnant or of childbearing potential and not on a reliable form of birth control.
- •Allergic to skin patch electrodes.
- •Vulnerable populations (fetuses, neonates, pregnant women, prisoners, institutionalized individuals).
结局指标
主要结局
Change in LF/HF ratio
时间窗: Baseline, 24 hours post catheter ablation and approximately 3-6 months post-operative
low frequency (LF)/high frequency (HF) ratio of the skin sympathetic nerve activity
Change in amplitude of skin sympathetic nerve activity
时间窗: Baseline, 24 hours post catheter ablation and approximately 3-6 months post-operative
measured in µV
次要结局
未报告次要终点
研究者
研究点 (1)
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