ISRCTN14884558已完成4 期
Targeting systemic inflammation to improve endothelial function in obesity
niversity of Leeds (UK)0 个研究点目标入组 50 人开始时间: 2011年6月10日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age 18-65
- •2. Obesity (Body Mass Index 30 or greater)
- •3. Not taking other medication (apart from oral contraceptives)
- •Target Gender: Male & Female; Upper Age Limit 65 years ; Lower Age Limit 18 years
排除标准
- •1. Diabetes
- •2. Hypertension
- •3. Hyperlipidaemia
- •4. Cardiovascular disease or history of cardiac arrythmias
- •5. Chronic inflammatory disorders (e.g. rheumatoid arthritis, connective tissue disorders, gout, inflammatory bowel
- •disease, chronic infections)
- •6. Acute inflammatory illnesses (e.g. upper respiratory tract infections)
- •7. Allergy to pentoxifylline or other methyl xanthine drugs or concomitant use of sildenafil, tadalafil, vardenafil or other phosphodiesterase inhibitors
- •8. History of cerebral haemorrhage or retinal haemorrhage
- •9. Pregnancy or breastfeeding
- •10. Impaired renal function
研究者
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