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临床试验/NCT03205813
NCT03205813已完成不适用

Prospective Study of Pain After Spinal Morphine for Cesarean Section and Analysis of Factors Involved in Moderate to Severe Pain

Mahidol University1 个研究点 分布在 1 个国家目标入组 660 人开始时间: 2017年7月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
660
试验地点
1
主要终点
Incidence of moderate to severe pain

研究概览

简要总结

Spinal block with intrathecal morphine is a popular anesthetic technique in cesarean delivery. This technique brings about good maternal and neonatal outcomes as well as provides good postoperative pain control. Systematic review showed intrathecal morphine produced long period of pain control up to 27 hours. However, some patients still experienced moderate to severe pain which defined as postoperative pain score >,= 4. From our institute survey, there were more than 50 percents of patients undergoing cesarean delivery receiving spinal block with intrathecal morphine experienced moderate to severe pain in the first 24 hours.

The aim of the study is to determine the actual incidence and associated factors of patients whom experienced moderate to severe pain after spinal anesthesia with intrathecal morphine 200 mcg in cesarean delivery.

详细描述

Spinal block with intrathecal morphine is a popular anesthetic technique in cesarean delivery. This technique brings about good maternal and neonatal outcomes as well as provides good postoperative pain control. Systematic review showed intrathecal morphine produced long period of pain control up to 27 hours. However, some patients still experienced moderate to severe pain which defined as postoperative pain score >,= 4. From our institute survey, there were more than 50 percents of patients undergoing cesarean delivery receiving spinal block with intrathecal morphine experienced moderate to severe pain in the first 24 hours. Failure in achieve adequate pain control results in poor maternal satisfaction, effect breast feeding and may lead to chronic wound pain.

The aim of the study is to determine the actual incidence of patients whom experienced moderate to severe pain after spinal anesthesia with intrathecal morphine 200 mcg in cesarean delivery. Also, factors that may involved moderate to severe postoperative pain will be analyzed and reported.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Age > 18 years
  • Elective cesarean section
  • Patient accept spinal anesthesia
  • ASA classification I-II
  • Understand numerical rating scale for pain score

排除标准

  • Not understand Thai
  • Contraindicated in spinal anesthesia with intrathecal morphine
  • Complicated pregnancy that general anesthesia may required for cesarean delivery

结局指标

主要结局

Incidence of moderate to severe pain

时间窗: The first 24 hours postoperatively

Incidence of moderate to severe pain, pain score \>,= 4

次要结局

  • Incidence of moderate to severe pain in the 2nd postoperative day(Form 24 hours to 48 hours postoperatively)
  • Factors associated with moderate to severe pain(The first 24 hours postoperatively)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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