2024-520226-10-00招募中3 期
Evaluation of the efficacy of treatment with mucosal bacterial vaccines(autovaccines) versus suppressive antibiotic treatment in subjects with hip or knee prosthesis infections.
Instituto De Investigacion Marques De Valdecilla1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2025年1月23日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Clinical course: Presence of exudate, redness of the wound, pain, or other clinical signs of infection.
研究概览
简要总结
To study in patients with joint prosthesis infection with non-curative intent the clinical relevance of autovaccines administered through the sublingual mucosa in decreasing clinical symptoms and/or progression of infection.
入排标准
- 年龄范围
- 18 years 至 65+ years（18-64 Years, 65+ Years）
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years of age
- •Carriers of hip or knee prosthesis, diagnosed with an active infection
- •Without the possibility of curative treatment
- •Patients who sign the informed consent form
- •Monomicrobial infections
排除标准
- •Patients with the possibility of curative treatment
- •Patients under 18 years of age
- •Polymicrobial infections
- •Fungal or mycobacterial infections
- •Patients with oral corticosteroids with doses higher than 5 mg/day in the three months prior to inclusion
结局指标
主要结局
Clinical course: Presence of exudate, redness of the wound, pain, or other clinical signs of infection.
Clinical course: Presence of exudate, redness of the wound, pain, or other clinical signs of infection.
次要结局
- Safety assessment: local and systemic adverse events
研究者
mar garcia
Scientific
Instituto De Investigacion Marques De Valdecilla
研究点 (1)
Loading locations...
相似试验
招募中
4 期
Vancomycin in TKAsNCT07282782University of California, San Diego30
Enrolling By Invitation
不适用
Implant-Related Infections in Patients With Skeletal SarcomasNCT07264296Vastra Gotaland Region40
已完成
不适用
A Study Comparing Two Different Denture Base Materials in Implant Retained OverdenturesNCT07271641Al-Azhar University16
招募中
3 期
Efficacy and safety of different antimicrobial DURATions for the treatment of Infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM). Phase 3 pragmatic multicenter open labelled randomized trial.2023-508442-18-00Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud De Sevilla364
招募中
不适用
One-stage Exchange in Candida Periprosthetic Infection a Suitable Way to goNCT07303101University Hospital, Strasbourg, France16