Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 510,000
- 试验地点
- 1
- 主要终点
- Major adverse cardiovascular event (MACE)
研究概览
简要总结
Cancer and cardiovascular disease are the global leading causes of death. These two disease entities are multifactorial disease that are caused by several factors. The aim of this prospective cohort study was to investigate the status of risk factors profiles and health related behavior in Korean population, and to discover novel risk factors associated with the occurrence of endpoint events.
详细描述
This is a single center, observational, prospective cohort study. The primary outcomes include the incidence of MACE (major adverse cardiovascular events) and the incidence of any malignancy. We plan to collect the baseline information at enrollment and the occurrence of clinical endpoint events will be followed for at least 10 years. The study will enroll 510,000 subjects aged ≥19 years who underwent a general health screening in Korea.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men or women aged 19 years and older who underwent a general health screening at the health promotion center of Ulsan University Hospital (Ulsan, Korea)
- •Subjects have to agree to participate by signing a consent
排除标准
- •Subjects who cannot or reject to sign the consent form.
结局指标
主要结局
Major adverse cardiovascular event (MACE)
时间窗: 10 year
A major adverse cardiovascular event (MACE) of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke
Incidence of malignancy
时间窗: 10 year
The occurrence of any malignancy of interest
次要结局
- Cardiovascular death(10 year)
- Myocardial infarction(10 year)
- Stroke(10 year)
- All-cause death(10 year)
- Cancer related mortality(10 year)
研究者
Sangwoo Park
MD
Ulsan University Hospital