NCT04734340Unknown不适用
The Study of EIT-guided Ventilation Strategy on ARDS Patients
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- ventilation free days
研究概览
简要总结
This study is a clinical randomized controlled study.The objective of this study is to compare the prognosis of patients with ARDS between eit-v / q-oriented individualized ventilation strategy and traditional lung protection ventilation strategy, and to establish the demonstration application of eit-v / q-oriented ventilation strategy in ARDS
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •According to ARDS Berlin standard, ARDS, PaO2 / FiO2 < 200mmhg, peep > 5cmh2o;
- •According to clinical judgment, lung recruitment therapy is needed due to hypoxemia;
- •The subjects or their families signed informed consent.
- •Admission to ICU was less than 72 hours;
- •The estimated duration of mechanical ventilation was more than or equal to 48 hours;
- •Age ≥ 18 years old and ≤ 80 years old;
排除标准
- •The patients with heart implants could not be monitored by EIT;
- •Patients or their families refused to participate in the study;
- •Hypernatremia
研究组 & 干预措施
EIT-guided group
Experimental
Treatment based on EIT
干预措施: EIT-guided PEEP setting (Procedure)
Control group
Placebo Comparator
Treatment based on ARDS-net Peep setting
干预措施: ARDS-net PEEP setting (Procedure)
结局指标
主要结局
ventilation free days
时间窗: 1 Day
次要结局
- 28-day mortality(28 days)
研究者
研究点 (1)
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