NCT01978665已完成4 期
The Effect of Prednisone and Solu-Medrol on Physical Exercise in COPD Patients and the Inflammaroty Response During and After Exercis.
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- effect on muscle power
研究概览
简要总结
The objective of this study is to investigate if there is an effect on exercise performance og of the anti inflammatory drugs prednisone and solu-medrol in patints with chronic obstructive pulmonary disease(COPD)
详细描述
RCT study with 4 days of steroid
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •FEV1< 60% FEV1/FVC ratio <70 %
- •able to use a ergometer bike
排除标准
- •Haemodynamicaly unstable heart conditions
- •exacerbations before 6 week entry of the study exacerbation during the study period treatment with beta blockers malignancy the last 5 years allergi toward IMP
研究组 & 干预措施
prednisone and Solumedrol
Placebo Comparator
placebo arm versus prednisone
干预措施: prednisone (Drug)
solumedrol
Placebo Comparator
placebo versus solu medrol
干预措施: prednisone (Drug)
placebo
Other
measurement of fitness
干预措施: prednisone (Drug)
结局指标
主要结局
effect on muscle power
时间窗: jan 2013 to july 2013 (6 months)
muscular strenght
次要结局
- the inflammatory response(jan 2013 to july 2013 (6 months))
研究者
Vibeke Backer
professor
Bispebjerg Hospital
研究点 (1)
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