临床试验/NCT05718986

NCT05718986尚未招募不适用

Epidemiology of Familial B-cell Lymphoproliferative Disorders

University of Haifa0 个研究点目标入组 1,000 人开始时间: 2024年6月最近更新: 2024年5月8日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: University of Haifa
入组人数: 1,000
主要终点: Prevalence of familial LPD in Israel

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

This study investigates families with at least two cases of B-cell lymphoproliferative disorders (LPD), and evaluates the prevalence of LPD in families, the relationship between medical history, genetic factors, and the risk of familial LPD, and various clinical outcomes for these families in a multiethnic population of Jews and Arabs in Israel.

研究设计

研究类型: Observational
观察模型: Family Based
时间视角: Other

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Patient inclusion criteria:
•Patients must have LPD and must have a family history of LPD. LPD patients who signed an informed consent to participate in the study.
•Criteria for the inclusion of relatives of patients:
•Relatives must be related by blood to LPD patients or unrelated (for control group).
•Relatives who signed an informed consent to participate in the study.

排除标准

•Pregnant women, special populations and those lacking judgment will not be included

结局指标

主要结局

Prevalence of familial LPD in Israel

时间窗: 5 years

Association between medical history and genetic variants and the risk of familial LPD

时间窗: 5 years

Risk of clinical outcomes among familial LPD and family members

时间窗: 15 years

次要结局

未报告次要终点

研究者

发起方

University of Haifa

申办方类型

Other

责任方

Principal Investigator

主要研究者

Geffen Kleinstern

Senior Lecturer

University of Haifa

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