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临床试验/NCT07710898
NCT07710898已完成不适用

Amelioration of Lipid Profile Through Date Cider-vinegar Along With 5:2 Intermittent Fasting Among Prediabetic Individuals

University of Lahore1 个研究点 分布在 1 个国家目标入组 108 人开始时间: 2026年1月12日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
108
试验地点
1
主要终点
Body Mass Index

研究概览

简要总结

A common metabolic abnormality in hyperglycemic individuals, dyslipidemia is strongly linked to an increased risk of cardiovascular illness. This study looked at how date cider vinegar and 5:2 intermittent fasting affected the lipid profile and metabolic indices of hyperglycemic patients

详细描述

The target population was adults between the ages of 35 and 65 years who are receiving outpatient care at a hospital or clinic with a diagnosis of either mild to moderate hypertension, dyslipidemia or pre-diabetes. Once consent was given, participants were then be randomly assigned to receive the prescribed intervention or act as a control. The intervention period was 12 weeks.

Participants in the experimental groups received date cider vinegar supplementation, with one group additionally following the 5:2 intermittent fasting protocol. The control group received standard dietary advice without vinegar supplementation or fasting intervention. Participants were instructed to follow the assigned intervention daily according to the study protocol. Weekly follow-up visits were conducted to monitor dietary compliance, record self-reported adherence, and assess health outcomes including lipid profile, body weight,and blood pressure. Usual dietary intake was also monitored to ensure consistency and adherence to the intervention.

At baseline, nutritional assessment based on weight and height, BMI, waist circumference, blood pressure, fasting blood glucose, lipid panels (HDL, LDL, total cholesterol, triglycerides), and dietary intake analysis were done. After 12 weeks of intervention all the measurements that were done again to compare the results pre- and post-intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
35 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The inclusion criterion was target adults with both gender aged 35-65 years.
  • Adults with a diagnosis of mild to moderate hypertension
  • Mild hypertension (140-159/90-99 mm Hg)
  • Moderate hypertension (160-179/100-109 mm Hg)
  • Adults having mild to moderate alterations in lipid profile
  • Triglycerides: 150 to 499 mg/dL
  • LDL-C levels: Mild Alteration (130 to 159 mg/dL) and Moderate Alteration (160 to 189 mg/dL)
  • Adults with pre-diabetes (hbA1c= 5.6-6.4%) were used.
  • Patients were solicited from hospital.

排除标准

  • Any Lactating and pregnant women were not included.
  • Any person allergic to citric acid.
  • Adults suffering from critical health conditions, including cancer.

结局指标

主要结局

Body Mass Index

时间窗: 3 months

BMI was calculated by dividing weight (in kg) by the square of height (in meters).

次要结局

  • Blood pressure(3 months)
  • Lipid Profile(3 months)

研究者

发起方
University of Lahore
申办方类型
Other
责任方
Principal Investigator
主要研究者

Maria Aslam

Clinical Head

University of Lahore

研究点 (1)

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