HIV Infection Accompanied by Multi-Drug Resistant Tuberculosis: a Decadal Systematic Review and Meta-Analysis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 222,128
- 试验地点
- 1
- 主要终点
- Prevalence of Multi-Drug Resistant Tuberculosis (MDR-TB) in HIV-Positive Patients
研究概览
简要总结
This study aims to investigate the relationship between HIV infection and multi-drug resistant tuberculosis (MDR-TB) among affected individuals in Zahedan, Iran. It will involve a detailed analysis of patient demographics, clinical characteristics, and treatment outcomes to enhance understanding of this co-infection. The findings may inform better treatment strategies and healthcare policies for managing these diseases in similar populations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (aged 18 years and older) diagnosed with both HIV and multi-drug-resistant tuberculosis (MDR-TB).
- •Studies published in peer-reviewed journals.
- •Studies that provide data on the co-occurrence of HIV and MDR-TB.
- •Participants from diverse geographical regions to enhance generalizability.
- •Studies with clear definitions of MDR-TB according to WHO guidelines.
排除标准
- •Studies that focus solely on drug-susceptible tuberculosis without MDR-TB.
- •Studies involving pediatric populations (under 18 years of age).
- •Non-original research such as reviews, editorials, and commentaries.
- •Studies lacking sufficient data on the co-occurrence of HIV and MDR-TB.
- •Studies that do not adhere to ethical guidelines for human subjects or lack appropriate ethical approvals.
结局指标
主要结局
Prevalence of Multi-Drug Resistant Tuberculosis (MDR-TB) in HIV-Positive Patients
时间窗: Data collected over the course of the studies from 2006 to 2018.
This study aims to determine the prevalence of multi-drug resistant tuberculosis (MDR-TB) among patients co-infected with HIV. Data will be collected from various studies included in the meta-analysis, focusing on the incidence rates of MDR-TB in this population. The analysis will provide insights into the challenges faced in treating HIV-positive individuals with MDR-TB and highlight the need for targeted interventions.
次要结局
未报告次要终点
研究者
Hamidreza Kouhpayeh
Assistant Professor
Zahedan University of Medical Sciences